
Supporting ambitious founders to multiply their impact
3 min
23 September 2025
Social entrepreneurs often have to navigate volatile contexts, operate with limited resources, and manage complex structures. They, therefore, need a community of high-impact enablers, especially individuals who have walked these journeys before.
Despite a growing ecosystem of bold, ambitious ventures, the path to scale remains hard. Social entrepreneurs often have to navigate volatile contexts, operate with limited resources, and manage complex structures. They therefore need a community of high-impact enablers, especially individuals who have walked these journeys before. 100x calls these individuals Multipliers.
Chesca Colloredo-Mansfeld, cofounder of Miracle Feet, is among 100x’s community of Multipliers who are supporting our global portfolio of impact ventures to navigate their scaling journeys.
Chesca brings a rich blend of corporate rigour and social sector experience to the 100x Multiplier community. Following a successful career in banking, consulting, and startups, she co-founded MiracleFeet, an NGO that has helped thousands of children access treatment for clubfoot.
Working with OneDay Health
For over a year, Chesca has worked closely with Nicolas Laing and Emma Ochoola, co-founders of OneDay Health, a 100x portfolio venture tackling healthcare blackholes in rural Uganda. A partnership grounded in mutual respect and hands-on support.
“It was never generic advice,” she says. “We tackled specific, timely issues from how to talk to funders to designing HR policies. And because I’d lived through many of these moments at MiracleFeet, I could say: here’s what we tried, here’s what worked, and here’s what didn’t.”
The strong alignment, paired with OneDay Health’s shared commitment to learning, created space for deep strategic thinking and meaningful progress.
"Working with Chesca has been a key highlight of our journey with 100x. Her deep experience, strategic insight, and practical support have saved us countless hours and helped us avoid mistakes we didn’t even know we were about to make.
“Having a trusted sounding board who’s walked this path before and truly understands the challenges of the work we do is truly valuable," says Nick.
The learning wasn’t one-way. Chesca describes gaining a great deal from OneDay Health, too, from the nuances of rural healthcare delivery in Uganda, to spirited debates around effective altruism and impact strategy.



100x’s flexible, venture-first, bespoke approach
One of the most powerful elements of the 100x Multiplier model, Chesca believes, is its flexibility. While the match with OneDay Health lent itself to regular touchpoints, other relationships, like those with Brazilian public policy venture ImpulsoGov, are more ad hoc and driven by specific needs as they arise.
“It only works when the organisation leads the way in shaping the relationship,” she says. “100x gets that, so it’s not a rigid programme but a resource, used with intention.”
Through the 100x Multiplier community, world-class experts and practitioners can work with some of the best founders and high-potential ventures solving the world’s toughest challenges.
“It’s an incredibly efficient way for anyone who cares about impact to maximise their influence,” Chesca adds. “A one-hour call with a founder can save them days of work or help them avoid a pitfall we fell into at MiracleFeet. That’s powerful.”
Speaking about their partnership with Alison Bukhari—UK Director of Educate Girls, Joao Abreu, co-founder of ImpulsoGov said:
“Beyond the renewed energy, with Alison and other Multipliers, we also learnt how other, world-class organisations work and can constantly benchmark to make improvements in both our strategy and operations"